POSITION TITLE: Research Associate
EDUCATION/TRAINING:
University of Ulm
Vordiplom: Biology, 1978
University of Munich
Ph.D. Biology, 1986
Princeton University
Postdoc: Biology, 1989
University of Utah
Postdoc: Biology, 1992
Research/Professional Experience
Washington State University, 1992-1995
Research Associate in the Department of Genetics and Cell
Biology, September 1992 to March 1993
Washington State University
Research Associate in the USDA/ARS unit, April 1993 to
April 1995
University of Idaho, 1995-1996
Research Associate in MMBB, May 1995 to November
1996
Washington State University, 1999-present
Project Associate Researcher in Dr. Michael Skinner's
laboratory
Publications
I.Sadler, K.Suda, G.Schatz, F.Kaudewitz, and A.Haid.
1984. Sequencing of the nuclear gene for the yeast
cytochrome c1 precursor reveals an unusually complex
amino-terminal presequence. EMBO J. 3, 2137-2143.
P.A.Silver, A.Chiang, and I.Sadler. 1988. Mutations that
alter both localization and production of a yeast nuclear
protein. Genes and Development 2, 707-717.
P.A.Silver, I.Sadler, and M.Osborne. 1989. Yeast proteins
that recognize nuclear localization sequences. J.Cell
Biol. 109, 983-989.
I.Sadler, A.Chiang, T.Kurihara, J.Rothblatt, J.Way, and
P.A.Silver. 1989. A yeast protein important for protein
assembly into the endoplasmic reticulum and the nucleus
has homology to DNA J, an E.coli heat shock protein.
J.Cell Biol. 109, 2665-2675.
I.Sadler, A.W.Crawford, J.Michelsen, and M.C.Beckerle.
1992. Zyxin and cCRP: Two interactive LIM domain proteins
associated with the cytoskeleton. J.Cell Biol. 119,
1573-1587.
K.I.O'Rourke, T.V.Baszler, J.M.Miller, T.R.Spraker,
I.Sadler-Riggleman, and D.P.Knowles. 1998. Monoclonal
antibody F89/160.1.5 defines a conserved epitope on the
ruminant prion protein. J.Clin.Microbiol.36(6),
1750-1755
Nilsson, E, Westfall, S., Sadler-Riggleman, I, Larsen, T,
McDonald, C, and MK Skinner (2002) An In Vivo Mouse
Reproter Gene (Human seccreted Alkaline Phosphatase)
Model to Monitor Ovarian Tumor Growth and Response to
Therapeutics. Cancer Chemo & Pharmacology
49:93-100.
Chaudhary, J., Sadler-Riggleman, I and Skinner, M.K.
(2004) Identification of a novel Sertoli cell gene
product SERT that influences follicle stimulating hormone
actions. Gene 324:79-88.
Saxlund MA, Sadler-Riggleman I, and MK Skinner (2004)
Role of Basic Helix-Loop-Helix (bHLH) and CREB
Transcription Factors in the Regulation of Sertoli Cell
Androgen Binding Protein Expression. Molecular
Reproduction and Development 68:269-278.
Chaudhary J, Sadler-Riggleman I and MK Skinner (2005) The
Helix-Loop-Helix Inhibitor of Differentiation (Id)
Proteins Induce Post-Mitotic Terminally Differentiated
Sertoli Cells to Re-Enter the Cell Cycle and Proliferate.
Biology of Reproduction 72:1205-1217.
Muir T, Sadler-Riggleman I, Stevens JD, and MK Skinner
(2005) Role of the basic helix-loop-helix protein ITF2 in
the hormonal regulation of Sertoli Cell Differentiation.
Molecular Reproduction and Development 73:491-500.
Muir T, Sadler-Riggleman I, Stevens JD, and MK Skinner
(2005) Role of the basic helix-loop-helix transcription
factor, scleraxis, in the regulation of Sertoli cell
function and differentiation. Molecular
Endocrinology.19:2164-2174.
Skinner MK, Schmidt M, Savenkova M, Sadler-Riggleman I,
and EE Nilsson. (2006) Regulation of granulosa and theca
cell transcriptomes during ovarian antral follicle
development. Mol Reprod Dev. 75(9):1457-72.