Education/Training
University of Idaho, Moscow,
ID
B.S. + B.S. 1983
Bacteriology + An. Sci.
Washington State University, Pullman, WA
D.V.M.
1987 Veterinary Medicine
University of Idaho, Moscow,
ID
Ph.
D.
1992 Zoology (Devel. Biol.)
Work Experience:
1993 Instructor: School of Veterinary Medicine,
Washington State University, Pullman, WA.
Taught section on antibiotics in Veterinary Pharmacology
class.
92-96 Researcher: Dr. Robert Speth, Department of
Veterinary and Comparative Anatomy, Physiology
and Pharmacology, Washington State University, Pullman,
WA.
Performed studies on the effects of the drug Quinaprill
on reproductive cyclicity of brain hormone
receptors using receptor binding assays, autoradiography,
computer image analysis and statistical
analysis.
96-98 Post Doctoral Fellow: Yamamoto Behavior Genes
Project, ERATO, Mitsubishi-kasei Institute of
Life Sciences, Machida-shi, Tokyo, Japan
Conducted study on the mechanisms by which genes control
sexual behavior in Drosophila
melanogaster making use of ectopic transgene expression,
immunocytochemistry, in-situ
hybridization and behavioral analysis.
98-99 Post Doctoral Fellow: Dr. Grant Mastick, Biology,
University of Nevada at Reno, Reno, NV.
Perform developmental biology studies on the control of
axon pathfinding in early mouse brain.
Immunocytochemical examination of the day 10.5 neural
tube to detect transcription factors and
surface molecules. In addition, a post-implantation
embryo culture system and electroporation
transgenesis system was developed to ectopically express
selected genes.
99- Research Associate: Dr. Michael K. Skinner, School of
Molecular Bioscience, Washington State
University, Pullman, WA. Perform studies to determine the
signaling factors which effect ovarian
and follicular development in mammals. Also, perform
pilot studies on treatments for ovarian cancer
in the nude mouse model.
Honors:
Jacob Monson Scholarship: 1978 and 1979
American Society of Animal Science Scholarship:
1983
Publications:
Nilsson, Eric E. and J. G. Cloud. (1992) “Rainbow
Trout chimeras produced by injection of blastomeres
into recipient blastulae.” Proc. Natl. Acad. Sci.,
USA. 89:9425-9428.
Nilsson, Eric E. and J. G. Cloud. (1993) “Extent of
mosaicism in experimentally produced
diploid/triploid
chimeric trout.” J. Exp. Zool. 226:47-50.
Nilsson, Eric E. and J. G. Cloud. (1993)
“Cryopreservation of rainbow trout (Oncorhynchus
mykiss)
blastomeres.” Aquat. Living Resour.
6(1):77-80.
Ragsdale, Frances R., Kevin M. Imel, Eric E. Nilsson and
Rolf l. Ingermann. (1993)
“Pregnancy-associated
factors affecting organic phosphate levels and oxygen
affinity of garter snake red cells.” General
and
Comp. Endocrin. 91:181-188.
Nilsson, Eric E., Zoltan Asztalos, Tamas Lukacsovich,
Wakae Awano, Kei Ito and Daisuke Yamamoto.
(2000) “Fruitless is in the regulatory pathway by
which ectopic mini-white and transformer induce
bisexual courtship in Drosophila.” J. Neurogenetics
13(4): 213-232.
Usui-Aoki, K., Hiroki Ito, Kumiko Ui-Tei, Tamas
Lukacsovich, Wakae Awano, Hiromi Nakata, Zheng Fu
Piao, Eric E. Nilsson, Jun-ya Tomida, Kuniaki Takahashi,
and Daisuke Yamamoto (2000)
“Formation of the male-specific muscle in female
Drosophila by ectopic fruitless expression.”
Nature Cell Biology 2:500-506.
Nilsson E., Parrott, J. and Skinner M.K. (2001) Basic
Fibroblast Growth Factor Induces
Primordial Follicle Development and Initiates
Folliculogenesis. Molec. & Cellular
Endocrinology
175:123-130
Nilsson E. and Skinner MK (2001) Cellular interactions
that control primordial follicle
development and folliculogenesis. Journal Society
Gynecologic Investigation 8:S1-S68.
Parrott JA, Nilsson, E. Mosher R., Magrane G., Albertson
D., Pinkel D., Gray JW, and Skinner M.K. (2001)
Stromal epithelial interactions in the progression of
ovarian cancer: Influence and source of tumor
stromal cells. Molecular and Cellular Endocrinology
175:29-39
Nilsson, E., Doraiswamy V., Parrott, J.A., and Skinner,
M.K. (2001) Expression and Action
of Transforming Growth Factor Beta (TGFβ1,
TGFβ2, TGFβ3) In Normal Ovarian Surface
Epithelium
and Ovarian Cancer. Molecular and Cellular Endocrinology
182:145-155.
Nilsson EE, Kezele P, Skinner MK (2002) Leukemia
inhibitory factor (LIF) promotes the primordial to
primary follicle transition in rat ovaries. Mol Cell
Endocrinol. 188(1-2):65-73.
Kezele P.R., Nilsson, E.E., and MK Skinner (2002) Insulin
But Not Insulin-like Growth Factor – 1
Promotes the Primordial to Primary Follicle Transition.
Biology of Reproduction 192(1-2):37-43.
Nilsson, E., S. Westfall, I. Sadler-Riggleman, T. Larsen,
C. McDonald and MK Skinner (2002) An In Vivo
Mouse Reporter Gene (Human Secreted Alkaline Phosphatase)
Model to Monitor Ovarian Tumor
Growth and Response to Therapeutics. Cancer Chemo &
Pharmacology. 49(2):93-100.
Nilsson EE, Skinner MK. (2002) Role of transforming
growth factor beta in ovarian surface epithelium
biology and ovarian cancer. Reprod Biomed
5(3):254-8.
Nilsson EE, Skinner MK. (2002) Growth and differentiation
factor-9 stimulates progression of early
primary but not primordial rat ovarian follicle
development. Biol Reprod. 67(3):1018-24.
Kezele PR, Nilsson EE, Skinner MK. (2002) Insulin but not
insulin-like growth factor-1 promotes the
primordial to primary follicle transition. Mol Cell
Endocrinol. 192(1-2):37-43.
Nilsson EE, Kezele P, Skinner MK. (2002) Leukemia
inhibitory factor (LIF) promotes the primordial to
primary follicle transition in rat ovaries. Mol Cell
Endocrinol. 188(1-2):65-73.
Nilsson EE, Westfall SD, McDonald C, Lison T,
Sadler-Riggleman I, Skinner MK. (2002) An in vivo
mouse
reporter gene (human secreted alkaline phosphatase) model
to monitor ovarian tumor growth and response to
therapeutics. Cancer Chemother Pharmacol.
49(2):93-100.
Nilsson EE, Skinner MK. (2003) Bone morphogenetic
protein-4 acts as an ovarian follicle survival
factor
and promotes primordial follicle development. Biol
Reprod. 69(4):1265-72.
Nilsson EE, Doraiswamy V, Skinner MK. (2003) Transforming
growth factor-beta isoform expression
during bovine ovarian antral follicle development. Mol
Reprod Dev. 66(3):237-46.
Nilsson EE, and Skinner MK. (2004) Kit Ligand and basic
fibroblast growth factor interactions in the
induction of ovarian primordial to primary follicle
transition. Molecular & Cellular Endocrinology
214:19-
25.
Nilsson EE, and Skinner MK. (2004) Kit Ligand and basic
fibroblast growth factor interactions in the
induction of ovarian primordial to primary follicle
transition. Mol Cell Endocrinol 214:19-25.
Kezele PR, Ague J, Nilsson EE and MK Skinner (2005)
Alterations in the ovarian transcriptome during
primordial follicle assembly and development. Biology of
Reproduction 72:241-255.
Kezele P, Nilsson EE and MK Skinner (2005) Keratinocyte
growth factor acts as a mesenchymal factor to promote
ovarian primordial to primary follicle transition.
Endocrinology (In Press).
Westfall S, Nilsson EE and MK Skinner (2005) Triptolide
as a potential chemotherapeutic for ovarian
cancer. Molecular Cancer Therapeutics (Submitted).